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Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway
Amyloidogenesis is known to cause Alzheimer’s disease. Our previous studies have found that lipopolysaccharide (LPS) causes neuroinflammation and amyloidogenesis through activation of nuclear factor kappaB (NF-κB). Piperlongumine (PL) is an alkaloid amide found naturally in long pepper (Piper longum...
Autores principales: | Gu, Sun Mi, Lee, Hee Pom, Ham, Young Wan, Son, Dong Ju, Kim, Hoi Yeong, Oh, Ki Wan, Han, Sang-Bae, Yun, Jaesuk, Hong, Jin Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097046/ https://www.ncbi.nlm.nih.gov/pubmed/29802525 http://dx.doi.org/10.1007/s12017-018-8495-9 |
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