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Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway

Amyloidogenesis is known to cause Alzheimer’s disease. Our previous studies have found that lipopolysaccharide (LPS) causes neuroinflammation and amyloidogenesis through activation of nuclear factor kappaB (NF-κB). Piperlongumine (PL) is an alkaloid amide found naturally in long pepper (Piper longum...

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Detalles Bibliográficos
Autores principales: Gu, Sun Mi, Lee, Hee Pom, Ham, Young Wan, Son, Dong Ju, Kim, Hoi Yeong, Oh, Ki Wan, Han, Sang-Bae, Yun, Jaesuk, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097046/
https://www.ncbi.nlm.nih.gov/pubmed/29802525
http://dx.doi.org/10.1007/s12017-018-8495-9

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