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Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018)
A tumor vascular‐targeted interlocking trimodal nanosystem that induces and exploits hypoxia is described by Hong‐Zhuan Chen, Chao Fang, and co‐workers in article number https://doi.org/10.1002/advs.201800034. In the image, the two streams of water from bamboo pipes and the rotary waterwheel are sho...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097092/ http://dx.doi.org/10.1002/advs.201870048 |
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author | Luan, Xin Guan, Ying‐Yun Liu, Hai‐Jun Lu, Qin Zhao, Mei Sun, Duxin Lovell, Jonathan F. Sun, Peng Chen, Hong‐Zhuan Fang, Chao |
author_facet | Luan, Xin Guan, Ying‐Yun Liu, Hai‐Jun Lu, Qin Zhao, Mei Sun, Duxin Lovell, Jonathan F. Sun, Peng Chen, Hong‐Zhuan Fang, Chao |
author_sort | Luan, Xin |
collection | PubMed |
description | A tumor vascular‐targeted interlocking trimodal nanosystem that induces and exploits hypoxia is described by Hong‐Zhuan Chen, Chao Fang, and co‐workers in article number https://doi.org/10.1002/advs.201800034. In the image, the two streams of water from bamboo pipes and the rotary waterwheel are shown to represent verteporfin for vascular‐targeted photodynamic treatment and HIF‐1α siRNA for elevated activating reductases (CYP450), which can trigger the activation of AQ4N (a hypoxia‐activated prodrug). [Image: see text] |
format | Online Article Text |
id | pubmed-6097092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-60970922018-08-20 Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018) Luan, Xin Guan, Ying‐Yun Liu, Hai‐Jun Lu, Qin Zhao, Mei Sun, Duxin Lovell, Jonathan F. Sun, Peng Chen, Hong‐Zhuan Fang, Chao Adv Sci (Weinh) Frontispiece A tumor vascular‐targeted interlocking trimodal nanosystem that induces and exploits hypoxia is described by Hong‐Zhuan Chen, Chao Fang, and co‐workers in article number https://doi.org/10.1002/advs.201800034. In the image, the two streams of water from bamboo pipes and the rotary waterwheel are shown to represent verteporfin for vascular‐targeted photodynamic treatment and HIF‐1α siRNA for elevated activating reductases (CYP450), which can trigger the activation of AQ4N (a hypoxia‐activated prodrug). [Image: see text] John Wiley and Sons Inc. 2018-08-17 /pmc/articles/PMC6097092/ http://dx.doi.org/10.1002/advs.201870048 Text en © 2018 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Frontispiece Luan, Xin Guan, Ying‐Yun Liu, Hai‐Jun Lu, Qin Zhao, Mei Sun, Duxin Lovell, Jonathan F. Sun, Peng Chen, Hong‐Zhuan Fang, Chao Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018) |
title | Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018) |
title_full | Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018) |
title_fullStr | Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018) |
title_full_unstemmed | Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018) |
title_short | Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018) |
title_sort | trimodal therapy: a tumor vascular‐targeted interlocking trimodal nanosystem that induces and exploits hypoxia (adv. sci. 8/2018) |
topic | Frontispiece |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097092/ http://dx.doi.org/10.1002/advs.201870048 |
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