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Persistent synovial inflammation plays important roles in persistent pain development in the rat knee before cartilage degradation reaches the subchondral bone

BACKGROUND: The major complaint of knee osteoarthritis (OA) is persistent pain. Unlike acute inflammatory pain, persistent pain is usually difficult to manage since its pathology is not fully understood. To elucidate the underlying mechanisms of persistent pain, we established 2 different inflammati...

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Detalles Bibliográficos
Autores principales:	Hoshino, Takashi, Tsuji, Kunikazu, Onuma, Hiroaki, Udo, Mio, Ueki, Hiroko, Akiyama, Masako, Abula, Kahaer, Katagiri, Hiroki, Miyatake, Kazumasa, Watanabe, Toshihumi, Sekiya, Ichiro, Koga, Hideyuki, Muneta, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097215/ https://www.ncbi.nlm.nih.gov/pubmed/30115046 http://dx.doi.org/10.1186/s12891-018-2221-5

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