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Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo
BACKGROUND: Abnormal expression of major histocompatibility complex class I (MHC-I) is increased in dopaminergic (DA) neurons in the substantia nigra (SN) in Parkinson’s disease (PD). Low-molecular-mass protein 7 (β5i) is a proteolytic subunit of the immunoproteasome that regulates protein degradati...
Autores principales: | Mo, Ming-Shu, Li, Gui-Hua, Sun, Cong-Cong, Huang, Shu-Xuan, Wei, Lei, Zhang, Li-Min, Zhou, Miao-Miao, Wu, Zhuo-Hua, Guo, Wen-Yuan, Yang, Xin-Ling, Chen, Chao-Jun, Qu, Shao-Gang, He, Jian-Xing, Xu, Ping-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097308/ https://www.ncbi.nlm.nih.gov/pubmed/30128145 http://dx.doi.org/10.1186/s40035-018-0125-9 |
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