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Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo

BACKGROUND: Abnormal expression of major histocompatibility complex class I (MHC-I) is increased in dopaminergic (DA) neurons in the substantia nigra (SN) in Parkinson’s disease (PD). Low-molecular-mass protein 7 (β5i) is a proteolytic subunit of the immunoproteasome that regulates protein degradati...

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Detalles Bibliográficos
Autores principales: Mo, Ming-Shu, Li, Gui-Hua, Sun, Cong-Cong, Huang, Shu-Xuan, Wei, Lei, Zhang, Li-Min, Zhou, Miao-Miao, Wu, Zhuo-Hua, Guo, Wen-Yuan, Yang, Xin-Ling, Chen, Chao-Jun, Qu, Shao-Gang, He, Jian-Xing, Xu, Ping-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097308/
https://www.ncbi.nlm.nih.gov/pubmed/30128145
http://dx.doi.org/10.1186/s40035-018-0125-9

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