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Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature

Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very...

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Autores principales: Palakshappa, Suhasini Gotur, Wadhwan, Vijay, Bansal, Vishal, Kamarthi, Nagaraju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097359/
https://www.ncbi.nlm.nih.gov/pubmed/30158793
http://dx.doi.org/10.4103/jomfp.JOMFP_70_16
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author Palakshappa, Suhasini Gotur
Wadhwan, Vijay
Bansal, Vishal
Kamarthi, Nagaraju
author_facet Palakshappa, Suhasini Gotur
Wadhwan, Vijay
Bansal, Vishal
Kamarthi, Nagaraju
author_sort Palakshappa, Suhasini Gotur
collection PubMed
description Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very difficult to diagnose MM in this region especially in patients with initial oral involvement. Furthermore, maxillofacial manifestations as an initial sign or symptom are scarce. We report a case of a 40-year-old male patient who presented with an unhealed socket in lower left back tooth region for the past 2 months. The panoramic radiograph revealed a multilocular radiolucency. Histopathological examination of the biopsy specimen revealed a malignant hematopoietic neoplasm formed by plasmacytoid cells. Radiographic survey and immunoreactivity for CD 138 and lambda chain antibody further confirmed the diagnosis of MM.
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spelling pubmed-60973592018-08-29 Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature Palakshappa, Suhasini Gotur Wadhwan, Vijay Bansal, Vishal Kamarthi, Nagaraju J Oral Maxillofac Pathol Case Report Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very difficult to diagnose MM in this region especially in patients with initial oral involvement. Furthermore, maxillofacial manifestations as an initial sign or symptom are scarce. We report a case of a 40-year-old male patient who presented with an unhealed socket in lower left back tooth region for the past 2 months. The panoramic radiograph revealed a multilocular radiolucency. Histopathological examination of the biopsy specimen revealed a malignant hematopoietic neoplasm formed by plasmacytoid cells. Radiographic survey and immunoreactivity for CD 138 and lambda chain antibody further confirmed the diagnosis of MM. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6097359/ /pubmed/30158793 http://dx.doi.org/10.4103/jomfp.JOMFP_70_16 Text en Copyright: © 2018 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Palakshappa, Suhasini Gotur
Wadhwan, Vijay
Bansal, Vishal
Kamarthi, Nagaraju
Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature
title Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature
title_full Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature
title_fullStr Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature
title_full_unstemmed Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature
title_short Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature
title_sort multiple myeloma presenting as an unhealed extraction socket: report of a case with brief review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097359/
https://www.ncbi.nlm.nih.gov/pubmed/30158793
http://dx.doi.org/10.4103/jomfp.JOMFP_70_16
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