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Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature
Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097359/ https://www.ncbi.nlm.nih.gov/pubmed/30158793 http://dx.doi.org/10.4103/jomfp.JOMFP_70_16 |
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author | Palakshappa, Suhasini Gotur Wadhwan, Vijay Bansal, Vishal Kamarthi, Nagaraju |
author_facet | Palakshappa, Suhasini Gotur Wadhwan, Vijay Bansal, Vishal Kamarthi, Nagaraju |
author_sort | Palakshappa, Suhasini Gotur |
collection | PubMed |
description | Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very difficult to diagnose MM in this region especially in patients with initial oral involvement. Furthermore, maxillofacial manifestations as an initial sign or symptom are scarce. We report a case of a 40-year-old male patient who presented with an unhealed socket in lower left back tooth region for the past 2 months. The panoramic radiograph revealed a multilocular radiolucency. Histopathological examination of the biopsy specimen revealed a malignant hematopoietic neoplasm formed by plasmacytoid cells. Radiographic survey and immunoreactivity for CD 138 and lambda chain antibody further confirmed the diagnosis of MM. |
format | Online Article Text |
id | pubmed-6097359 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-60973592018-08-29 Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature Palakshappa, Suhasini Gotur Wadhwan, Vijay Bansal, Vishal Kamarthi, Nagaraju J Oral Maxillofac Pathol Case Report Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very difficult to diagnose MM in this region especially in patients with initial oral involvement. Furthermore, maxillofacial manifestations as an initial sign or symptom are scarce. We report a case of a 40-year-old male patient who presented with an unhealed socket in lower left back tooth region for the past 2 months. The panoramic radiograph revealed a multilocular radiolucency. Histopathological examination of the biopsy specimen revealed a malignant hematopoietic neoplasm formed by plasmacytoid cells. Radiographic survey and immunoreactivity for CD 138 and lambda chain antibody further confirmed the diagnosis of MM. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6097359/ /pubmed/30158793 http://dx.doi.org/10.4103/jomfp.JOMFP_70_16 Text en Copyright: © 2018 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Palakshappa, Suhasini Gotur Wadhwan, Vijay Bansal, Vishal Kamarthi, Nagaraju Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature |
title | Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature |
title_full | Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature |
title_fullStr | Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature |
title_full_unstemmed | Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature |
title_short | Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature |
title_sort | multiple myeloma presenting as an unhealed extraction socket: report of a case with brief review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097359/ https://www.ncbi.nlm.nih.gov/pubmed/30158793 http://dx.doi.org/10.4103/jomfp.JOMFP_70_16 |
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