Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy

While generally benign, occasional aggressive histologic features in the melanotic neuroectodermal tumor of infancy (MNTI) have been used to justify a diagnosis of malignancy; this could lead to overtreatment. We report a case with presumed aggressive histologic features that did not recur following...

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Autores principales: Marschall, Jeffrey S, Kushner, George M, Shumway, Brian S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097382/
https://www.ncbi.nlm.nih.gov/pubmed/30158782
http://dx.doi.org/10.4103/jomfp.JOMFP_161_17
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author Marschall, Jeffrey S
Kushner, George M
Shumway, Brian S
author_facet Marschall, Jeffrey S
Kushner, George M
Shumway, Brian S
author_sort Marschall, Jeffrey S
collection PubMed
description While generally benign, occasional aggressive histologic features in the melanotic neuroectodermal tumor of infancy (MNTI) have been used to justify a diagnosis of malignancy; this could lead to overtreatment. We report a case with presumed aggressive histologic features that did not recur following conservative treatment. This adds evidence that histologic features are not predictive of clinical behavior in MNTI.
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spelling pubmed-60973822018-08-29 Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy Marschall, Jeffrey S Kushner, George M Shumway, Brian S J Oral Maxillofac Pathol Short Communication While generally benign, occasional aggressive histologic features in the melanotic neuroectodermal tumor of infancy (MNTI) have been used to justify a diagnosis of malignancy; this could lead to overtreatment. We report a case with presumed aggressive histologic features that did not recur following conservative treatment. This adds evidence that histologic features are not predictive of clinical behavior in MNTI. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6097382/ /pubmed/30158782 http://dx.doi.org/10.4103/jomfp.JOMFP_161_17 Text en Copyright: © 2018 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Short Communication
Marschall, Jeffrey S
Kushner, George M
Shumway, Brian S
Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy
title Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy
title_full Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy
title_fullStr Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy
title_full_unstemmed Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy
title_short Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy
title_sort aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097382/
https://www.ncbi.nlm.nih.gov/pubmed/30158782
http://dx.doi.org/10.4103/jomfp.JOMFP_161_17
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AT shumwaybrians aggressivehistologicfeaturesdonotpredictbiologicbehaviorinmelanoticneuroectodermaltumorofinfancy

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