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Adapted HCV JFH1 variant is capable of accommodating a large foreign gene insert and allows lower level HCV replication and viral production

Infectious HCV carrying reporter genes have further applications in understanding the HCV life cycle including replication, viral assembly and release. In this study, a full-length 3039bp LacZ gene was inserted into the derivative of JFH1-AM120 to develop an additional reporter virus. The results sh...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Hagedorn, Curt, Liu, Shuanghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097470/
https://www.ncbi.nlm.nih.gov/pubmed/30123070
http://dx.doi.org/10.7150/ijbs.27411