The increased release of amino acid neurotransmitters of the primary somatosensory cortical area in rats contributes to remifentanil-induced hyperalgesia and its inhibition by lidocaine

BACKGROUND: Studies have confirmed that activation of the neurons of primary somatosensory cortex (S1) is involved in the process of remifentanil (Remi)-induced hyperalgesia (RIH), which can be suppressed by lidocaine (Lido). A total intravenous anesthesia model of rats mimicking clinical Remi-based...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Cui, Weihua, Zeng, Min, Ren, Yi, Han, Song, Li, Junfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097504/
https://www.ncbi.nlm.nih.gov/pubmed/30147356
http://dx.doi.org/10.2147/JPR.S168008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097504/
https://www.ncbi.nlm.nih.gov/pubmed/30147356
http://dx.doi.org/10.2147/JPR.S168008

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