Cargando…
Class II HLA Genotype Association With First-Phase Insulin Response Is Explained by Islet Autoantibodies
CONTEXT: A declining first-phase insulin response (FPIR) is characteristic of the disease process leading to clinical type 1 diabetes. It is not known whether reduced FPIR depends on class II human leukocyte antigen (HLA) genotype, islet autoimmunity, or both. OBJECTIVE: To dissect the role of class...
Autores principales: | Koskinen, Maarit K, Lempainen, Johanna, Löyttyniemi, Eliisa, Helminen, Olli, Hekkala, Anne, Härkönen, Taina, Kiviniemi, Minna, Simell, Olli, Knip, Mikael, Ilonen, Jorma, Toppari, Jorma, Veijola, Riitta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097602/ https://www.ncbi.nlm.nih.gov/pubmed/29300921 http://dx.doi.org/10.1210/jc.2017-02040 |
Ejemplares similares
-
First-emerging islet autoantibody and glucose metabolism: search for type 1 diabetes subtypes
por: Helminen, Olli, et al.
Publicado: (2022) -
Early glucose metabolism in children at risk for type 1 diabetes based on islet autoantibodies compared to low-risk control groups
por: Helminen, Olli, et al.
Publicado: (2022) -
Effect of HLA Class I and Class II Alleles on Progression From Autoantibody Positivity to Overt Type 1 Diabetes in Children With Risk-Associated Class II Genotypes
por: Lipponen, Kati, et al.
Publicado: (2010) -
Predictive Characteristics of Diabetes-Associated Autoantibodies Among Children With HLA-Conferred Disease Susceptibility in the General Population
por: Siljander, Heli T.A., et al.
Publicado: (2009) -
Serum 25-Hydroxyvitamin D Concentrations at Birth in Children Screened for HLA-DQB1 Conferred Risk for Type 1 Diabetes
por: Mäkinen, Marjaana, et al.
Publicado: (2019)