Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations

Molecular subtypes of colorectal tumors are associated with prognosis and prediction for treatment benefit from chemotherapy. The purpose of this study was two-fold: 1) to determine the association of colorectal (CRC) molecular subtypes with response to targeted therapies in pre-clinical models and...

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Detalles Bibliográficos
Autores principales: Pal, Rekha, Wei, Ning, Song, Nan, Wu, Shaoyu, Kim, Rim S., Wang, Ying, Gavin, Patrick G., Lucas, Peter C., Srinivasan, Ashok, Allegra, Carmen J., Jacobs, Samuel A., Paik, Soonmyung, Schmitz, John C., Pogue-Geile, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097647/
https://www.ncbi.nlm.nih.gov/pubmed/30118499
http://dx.doi.org/10.1371/journal.pone.0200836

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