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Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils

Neutrophils and eosinophils are important sources of bioactive lipids from the 5- and the 15-lipoxygenase (LO) pathways. Herein, we compared the effectiveness of humans eosinophils and eosinophil-depleted neutrophils to synthesize 15-LO metabolites using a cocktail of different 15-LO substrates as w...

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Detalles Bibliográficos
Autores principales: Archambault, Anne-Sophie, Turcotte, Caroline, Martin, Cyril, Provost, Véronique, Larose, Marie-Chantal, Laprise, Catherine, Chakir, Jamila, Bissonnette, Élyse, Laviolette, Michel, Bossé, Ynuk, Flamand, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097673/
https://www.ncbi.nlm.nih.gov/pubmed/30118527
http://dx.doi.org/10.1371/journal.pone.0202424