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Characterizing the Relation Between Expression QTLs and Complex Traits: Exploring the Role of Tissue Specificity

Measurement of gene expression levels and detection of eQTLs (expression quantitative trait loci) are difficult in tissues with limited sample availability, such as the brain. However, eQTL overlap between tissues might be high, which would allow for inference of eQTL functioning in the brain via eQ...

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Detalles Bibliográficos
Autores principales: Ip, Hill F., Jansen, Rick, Abdellaoui, Abdel, Bartels, Meike, Boomsma, Dorret I., Nivard, Michel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097736/
https://www.ncbi.nlm.nih.gov/pubmed/30030655
http://dx.doi.org/10.1007/s10519-018-9914-2

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