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A current view on long noncoding RNAs in yeast and filamentous fungi

Long noncoding RNAs (lncRNAs) are crucial players in epigenetic regulation. They were initially discovered in human, yet they emerged as common factors involved in a number of central cellular processes in several eukaryotes. For example, in the past decade, research on lncRNAs in yeast has steadily...

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Detalles Bibliográficos
Autores principales: Till, Petra, Mach, Robert L., Mach-Aigner, Astrid R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097775/
https://www.ncbi.nlm.nih.gov/pubmed/29974182
http://dx.doi.org/10.1007/s00253-018-9187-y
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author Till, Petra
Mach, Robert L.
Mach-Aigner, Astrid R.
author_facet Till, Petra
Mach, Robert L.
Mach-Aigner, Astrid R.
author_sort Till, Petra
collection PubMed
description Long noncoding RNAs (lncRNAs) are crucial players in epigenetic regulation. They were initially discovered in human, yet they emerged as common factors involved in a number of central cellular processes in several eukaryotes. For example, in the past decade, research on lncRNAs in yeast has steadily increased. Several examples of lncRNAs were described in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Also, screenings for lncRNAs in ascomycetes were performed and, just recently, the first full characterization of a lncRNA was performed in the filamentous fungus Trichoderma reesei. In this review, we provide a broad overview about currently known fugal lncRNAs. We make an attempt to categorize them according to their functional context, regulatory strategies or special properties. Moreover, the potential of lncRNAs as a biotechnological tool is discussed.
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spelling pubmed-60977752018-08-24 A current view on long noncoding RNAs in yeast and filamentous fungi Till, Petra Mach, Robert L. Mach-Aigner, Astrid R. Appl Microbiol Biotechnol Mini-Review Long noncoding RNAs (lncRNAs) are crucial players in epigenetic regulation. They were initially discovered in human, yet they emerged as common factors involved in a number of central cellular processes in several eukaryotes. For example, in the past decade, research on lncRNAs in yeast has steadily increased. Several examples of lncRNAs were described in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Also, screenings for lncRNAs in ascomycetes were performed and, just recently, the first full characterization of a lncRNA was performed in the filamentous fungus Trichoderma reesei. In this review, we provide a broad overview about currently known fugal lncRNAs. We make an attempt to categorize them according to their functional context, regulatory strategies or special properties. Moreover, the potential of lncRNAs as a biotechnological tool is discussed. Springer Berlin Heidelberg 2018-07-04 2018 /pmc/articles/PMC6097775/ /pubmed/29974182 http://dx.doi.org/10.1007/s00253-018-9187-y Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Mini-Review
Till, Petra
Mach, Robert L.
Mach-Aigner, Astrid R.
A current view on long noncoding RNAs in yeast and filamentous fungi
title A current view on long noncoding RNAs in yeast and filamentous fungi
title_full A current view on long noncoding RNAs in yeast and filamentous fungi
title_fullStr A current view on long noncoding RNAs in yeast and filamentous fungi
title_full_unstemmed A current view on long noncoding RNAs in yeast and filamentous fungi
title_short A current view on long noncoding RNAs in yeast and filamentous fungi
title_sort current view on long noncoding rnas in yeast and filamentous fungi
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097775/
https://www.ncbi.nlm.nih.gov/pubmed/29974182
http://dx.doi.org/10.1007/s00253-018-9187-y
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