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Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study
Despite recent advances, chemoimmunotherapy remains a standard for fit previously untreated chronic lymphocytic leukaemia patients. Lenalidomide had activity in early monotherapy trials, but tumour lysis and flare proved major obstacles in its development. We combined lenalidomide in increasing dose...
Autores principales: | Egle, Alexander, Steurer, Michael, Melchardt, Thomas, Weiss, Lukas, Gassner, Franz Josef, Zaborsky, Nadja, Geisberger, Roland, Catakovic, Kemal, Hartmann, Tanja Nicole, Pleyer, Lisa, Voskova, Daniela, Thaler, Josef, Lang, Alois, Girschikofsky, Michael, Petzer, Andreas, Greil, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097797/ https://www.ncbi.nlm.nih.gov/pubmed/29862437 http://dx.doi.org/10.1007/s00277-018-3380-z |
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