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Three-level spaser for next-generation luminescent nanoprobe
The development of modern biological and medical science highly depends on advanced luminescent probes. Current probes typically have wide emission spectra of 30 to 100 nm, which limits the number of resolvable colors that are simultaneously labeled on samples. Spasers, the abbreviation for surface...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097815/ https://www.ncbi.nlm.nih.gov/pubmed/30128353 http://dx.doi.org/10.1126/sciadv.aat0292 |
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author | Song, Pei Wang, Jian-Hua Zhang, Miao Yang, Fan Lu, Hai-Jie Kang, Bin Xu, Jing-Juan Chen, Hong-Yuan |
author_facet | Song, Pei Wang, Jian-Hua Zhang, Miao Yang, Fan Lu, Hai-Jie Kang, Bin Xu, Jing-Juan Chen, Hong-Yuan |
author_sort | Song, Pei |
collection | PubMed |
description | The development of modern biological and medical science highly depends on advanced luminescent probes. Current probes typically have wide emission spectra of 30 to 100 nm, which limits the number of resolvable colors that are simultaneously labeled on samples. Spasers, the abbreviation for surface plasmon lasers, have ultranarrow lasing spectra by stimulated light amplification in the plasmon nanocavity. However, high threshold (>10(2) mJ cm(−2)) and short lasing lifetime (approximately picoseconds to nanoseconds) still remain obstacles for current two-level spaser systems. We demonstrated a new type of a three-level spaser using triplet-state electrons. By prolonging the upper state lifetime and controlling the energy transfer, high gain compensation was generated. This probe, named delayed spasing dots (dsDs), about 50 to 60 nm in size, exhibited a spectral linewidth of ~3 nm, an ultralow threshold of ~1 mJ cm(−2), and a delayed lasing lifetime of ~10(2) μs. As the first experimental realization of the three-level spaser system, our results suggested a general strategy to tune the spasing threshold and dynamics by engineering the energy level of the gain medium and the energy transfer process. These dsDs have the potential to become new-generation luminescent probes for super-multiplex biological analysis without disturbance from short lifetime background emission. |
format | Online Article Text |
id | pubmed-6097815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-60978152018-08-20 Three-level spaser for next-generation luminescent nanoprobe Song, Pei Wang, Jian-Hua Zhang, Miao Yang, Fan Lu, Hai-Jie Kang, Bin Xu, Jing-Juan Chen, Hong-Yuan Sci Adv Research Articles The development of modern biological and medical science highly depends on advanced luminescent probes. Current probes typically have wide emission spectra of 30 to 100 nm, which limits the number of resolvable colors that are simultaneously labeled on samples. Spasers, the abbreviation for surface plasmon lasers, have ultranarrow lasing spectra by stimulated light amplification in the plasmon nanocavity. However, high threshold (>10(2) mJ cm(−2)) and short lasing lifetime (approximately picoseconds to nanoseconds) still remain obstacles for current two-level spaser systems. We demonstrated a new type of a three-level spaser using triplet-state electrons. By prolonging the upper state lifetime and controlling the energy transfer, high gain compensation was generated. This probe, named delayed spasing dots (dsDs), about 50 to 60 nm in size, exhibited a spectral linewidth of ~3 nm, an ultralow threshold of ~1 mJ cm(−2), and a delayed lasing lifetime of ~10(2) μs. As the first experimental realization of the three-level spaser system, our results suggested a general strategy to tune the spasing threshold and dynamics by engineering the energy level of the gain medium and the energy transfer process. These dsDs have the potential to become new-generation luminescent probes for super-multiplex biological analysis without disturbance from short lifetime background emission. American Association for the Advancement of Science 2018-08-17 /pmc/articles/PMC6097815/ /pubmed/30128353 http://dx.doi.org/10.1126/sciadv.aat0292 Text en Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Song, Pei Wang, Jian-Hua Zhang, Miao Yang, Fan Lu, Hai-Jie Kang, Bin Xu, Jing-Juan Chen, Hong-Yuan Three-level spaser for next-generation luminescent nanoprobe |
title | Three-level spaser for next-generation luminescent nanoprobe |
title_full | Three-level spaser for next-generation luminescent nanoprobe |
title_fullStr | Three-level spaser for next-generation luminescent nanoprobe |
title_full_unstemmed | Three-level spaser for next-generation luminescent nanoprobe |
title_short | Three-level spaser for next-generation luminescent nanoprobe |
title_sort | three-level spaser for next-generation luminescent nanoprobe |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097815/ https://www.ncbi.nlm.nih.gov/pubmed/30128353 http://dx.doi.org/10.1126/sciadv.aat0292 |
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