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A discriminator code–based DTD surveillance ensures faithful glycine delivery for protein biosynthesis in bacteria
D-aminoacyl-tRNA deacylase (DTD) acts on achiral glycine, in addition to D-amino acids, attached to tRNA. We have recently shown that this activity enables DTD to clear non-cognate Gly-tRNA(Ala) with 1000-fold higher efficiency than its activity on Gly-tRNA(Gly), indicating tRNA-based modulation of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097841/ https://www.ncbi.nlm.nih.gov/pubmed/30091703 http://dx.doi.org/10.7554/eLife.38232 |