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Modified Fe(3)O(4) Magnetic Nanoparticle Delivery of CpG Inhibits Tumor Growth and Spontaneous Pulmonary Metastases to Enhance Immunotherapy

As a novel toll-like receptor 9 (TLR9) agonist, synthetic unmethylated cytosine-phosphate-guanine (CpG) oligodeoxynucleotides can stimulate a Th1 immune response and potentially be used as therapeutic agents or vaccine adjuvants for the treatment of cancer. However, some drawbacks of CpG limit their...

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Detalles Bibliográficos
Autores principales:	Zhang, Xueyan, Wu, Fengbo, Men, Ke, Huang, Rong, Zhou, Bailin, Zhang, Rui, Zou, Rui, Yang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Nano Idea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097979/ https://www.ncbi.nlm.nih.gov/pubmed/30120629 http://dx.doi.org/10.1186/s11671-018-2661-8

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