SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis

Regulation of VEGFR2 represents an important mechanism for the control of angiogenesis. VEGFR2 activity can be regulated by post-translational modifications such as ubiquitination and acetylation. However, whether VEGFR2 can be regulated by SUMOylation has not been investigated. Here we show that en...

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Detalles Bibliográficos
Autores principales: Zhou, Huanjiao Jenny, Xu, Zhe, Wang, Zongren, Zhang, Haifeng, Zhuang, Zhen W., Simons, Michael, Min, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098000/
https://www.ncbi.nlm.nih.gov/pubmed/30120232
http://dx.doi.org/10.1038/s41467-018-05812-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098000/
https://www.ncbi.nlm.nih.gov/pubmed/30120232
http://dx.doi.org/10.1038/s41467-018-05812-2

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