Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson’s disease models

An excess of reactive oxygen species (ROS) relative to the antioxidant capacity causes oxidative stress, which plays a role in the development of Parkinson’s disease (PD). Because mitochondria are both sites of ROS generation and targets of ROS damage, the delivery of antioxidants to mitochondria mi...

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Detalles Bibliográficos
Autores principales: Kang, Young Cheol, Son, Minuk, Kang, Sora, Im, Suyeol, Piao, Ying, Lim, Kwang Suk, Song, Min-Young, Park, Kang-Sik, Kim, Yong-Hee, Pak, Youngmi Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098059/
https://www.ncbi.nlm.nih.gov/pubmed/30120245
http://dx.doi.org/10.1038/s12276-018-0124-z

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