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Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil
In the present article we report the nearly full length genome of a Cosavirus strain (BRTO-83) isolated from a child with acute gastroenteritis, and who is an inhabitant of a rural area in the central region of Brazil. The sample was previously screened and negative for both: common enteric viruses...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098101/ https://www.ncbi.nlm.nih.gov/pubmed/30120342 http://dx.doi.org/10.1038/s41598-018-30214-1 |
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| author | da Costa, Antonio Charlys Luchs, Adriana Milagres, Flavio Augusto de Pádua Komninakis, Shirley Vasconcelos Gill, Danielle Elise Lobato, Márcia Cristina Alves Brito Sayão Brustulin, Rafael das Chagas, Rogério Togisaki Abrão, Maria de Fátima Neves dos Santos Soares, Cassia Vitória de Deus Alves Deng, Xutao Sabino, Ester Cerdeira Delwart, Eric Leal, Élcio |
| author_facet | da Costa, Antonio Charlys Luchs, Adriana Milagres, Flavio Augusto de Pádua Komninakis, Shirley Vasconcelos Gill, Danielle Elise Lobato, Márcia Cristina Alves Brito Sayão Brustulin, Rafael das Chagas, Rogério Togisaki Abrão, Maria de Fátima Neves dos Santos Soares, Cassia Vitória de Deus Alves Deng, Xutao Sabino, Ester Cerdeira Delwart, Eric Leal, Élcio |
| author_sort | da Costa, Antonio Charlys |
| collection | PubMed |
| description | In the present article we report the nearly full length genome of a Cosavirus strain (BRTO-83) isolated from a child with acute gastroenteritis, and who is an inhabitant of a rural area in the central region of Brazil. The sample was previously screened and negative for both: common enteric viruses (i.e. rotavirus and norovirus), bacteria, endoparasites and helminthes. Evolutionary analysis and phylogenetic inferences indicated that the Brazilian BRTO-83 Cosavirus strain was a recombinant virus highly related to the E/D recombinant NG385 strain (Genbank JN867757), which was isolated in Nigeria from an acute flaccid paralysis patient. This is the first report of a recombinant E/D Cosavirus strain detected in Brazil, and the second genome described worldwide. Further surveillance and molecular studies are required to fully understand the epidemiology, distribution and evolution of the Cosavirus. |
| format | Online Article Text |
| id | pubmed-6098101 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60981012018-08-23 Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil da Costa, Antonio Charlys Luchs, Adriana Milagres, Flavio Augusto de Pádua Komninakis, Shirley Vasconcelos Gill, Danielle Elise Lobato, Márcia Cristina Alves Brito Sayão Brustulin, Rafael das Chagas, Rogério Togisaki Abrão, Maria de Fátima Neves dos Santos Soares, Cassia Vitória de Deus Alves Deng, Xutao Sabino, Ester Cerdeira Delwart, Eric Leal, Élcio Sci Rep Article In the present article we report the nearly full length genome of a Cosavirus strain (BRTO-83) isolated from a child with acute gastroenteritis, and who is an inhabitant of a rural area in the central region of Brazil. The sample was previously screened and negative for both: common enteric viruses (i.e. rotavirus and norovirus), bacteria, endoparasites and helminthes. Evolutionary analysis and phylogenetic inferences indicated that the Brazilian BRTO-83 Cosavirus strain was a recombinant virus highly related to the E/D recombinant NG385 strain (Genbank JN867757), which was isolated in Nigeria from an acute flaccid paralysis patient. This is the first report of a recombinant E/D Cosavirus strain detected in Brazil, and the second genome described worldwide. Further surveillance and molecular studies are required to fully understand the epidemiology, distribution and evolution of the Cosavirus. Nature Publishing Group UK 2018-08-17 /pmc/articles/PMC6098101/ /pubmed/30120342 http://dx.doi.org/10.1038/s41598-018-30214-1 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Article da Costa, Antonio Charlys Luchs, Adriana Milagres, Flavio Augusto de Pádua Komninakis, Shirley Vasconcelos Gill, Danielle Elise Lobato, Márcia Cristina Alves Brito Sayão Brustulin, Rafael das Chagas, Rogério Togisaki Abrão, Maria de Fátima Neves dos Santos Soares, Cassia Vitória de Deus Alves Deng, Xutao Sabino, Ester Cerdeira Delwart, Eric Leal, Élcio Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil |
| title | Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil |
| title_full | Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil |
| title_fullStr | Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil |
| title_full_unstemmed | Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil |
| title_short | Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil |
| title_sort | near full length genome of a recombinant (e/d) cosavirus strain from a rural area in the central region of brazil |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098101/ https://www.ncbi.nlm.nih.gov/pubmed/30120342 http://dx.doi.org/10.1038/s41598-018-30214-1 |
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