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Epidemiological and cytogenetic profiles of patients with hematological malignancies and their relationship with aging

BACKGROUND: Hematologic neoplasms are associated with mutations in hematopoietic cells and chromosomal abnormalities. During aging, about 2–3% of the elderly have chromosomal abnormalities arising from clonal mosaicism, the immune system is impaired and the bone marrow loses its ability to replace b...

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Detalles Bibliográficos
Autores principales: Alves, Angelica de Souza Batista Maia, Bataglia, Fernanda Barbi, Conterno, Luciene de Oliveira, Segato, Rosimeire, Payão, Spencer Luiz Marques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098168/
https://www.ncbi.nlm.nih.gov/pubmed/30128427
http://dx.doi.org/10.1016/j.htct.2017.10.001