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Archaeal cell surface biogenesis

Cell surfaces are critical for diverse functions across all domains of life, from cell-cell communication and nutrient uptake to cell stability and surface attachment. While certain aspects of the mechanisms supporting the biosynthesis of the archaeal cell surface are unique, likely due to important...

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Detalles Bibliográficos
Autores principales: Pohlschroder, Mechthild, Pfeiffer, Friedhelm, Schulze, Stefan, Halim, Mohd Farid Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098224/
https://www.ncbi.nlm.nih.gov/pubmed/29912330
http://dx.doi.org/10.1093/femsre/fuy027
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author Pohlschroder, Mechthild
Pfeiffer, Friedhelm
Schulze, Stefan
Halim, Mohd Farid Abdul
author_facet Pohlschroder, Mechthild
Pfeiffer, Friedhelm
Schulze, Stefan
Halim, Mohd Farid Abdul
author_sort Pohlschroder, Mechthild
collection PubMed
description Cell surfaces are critical for diverse functions across all domains of life, from cell-cell communication and nutrient uptake to cell stability and surface attachment. While certain aspects of the mechanisms supporting the biosynthesis of the archaeal cell surface are unique, likely due to important differences in cell surface compositions between domains, others are shared with bacteria or eukaryotes or both. Based on recent studies completed on a phylogenetically diverse array of archaea, from a wide variety of habitats, here we discuss advances in the characterization of mechanisms underpinning archaeal cell surface biogenesis. These include those facilitating co- and post-translational protein targeting to the cell surface, transport into and across the archaeal lipid membrane, and protein anchoring strategies. We also discuss, in some detail, the assembly of specific cell surface structures, such as the archaeal S-layer and the type IV pili. We will highlight the importance of post-translational protein modifications, such as lipid attachment and glycosylation, in the biosynthesis as well as the regulation of the functions of these cell surface structures and present the differences and similarities in the biogenesis of type IV pili across prokaryotic domains.
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spelling pubmed-60982242018-08-22 Archaeal cell surface biogenesis Pohlschroder, Mechthild Pfeiffer, Friedhelm Schulze, Stefan Halim, Mohd Farid Abdul FEMS Microbiol Rev Review Article Cell surfaces are critical for diverse functions across all domains of life, from cell-cell communication and nutrient uptake to cell stability and surface attachment. While certain aspects of the mechanisms supporting the biosynthesis of the archaeal cell surface are unique, likely due to important differences in cell surface compositions between domains, others are shared with bacteria or eukaryotes or both. Based on recent studies completed on a phylogenetically diverse array of archaea, from a wide variety of habitats, here we discuss advances in the characterization of mechanisms underpinning archaeal cell surface biogenesis. These include those facilitating co- and post-translational protein targeting to the cell surface, transport into and across the archaeal lipid membrane, and protein anchoring strategies. We also discuss, in some detail, the assembly of specific cell surface structures, such as the archaeal S-layer and the type IV pili. We will highlight the importance of post-translational protein modifications, such as lipid attachment and glycosylation, in the biosynthesis as well as the regulation of the functions of these cell surface structures and present the differences and similarities in the biogenesis of type IV pili across prokaryotic domains. Oxford University Press 2018-06-15 /pmc/articles/PMC6098224/ /pubmed/29912330 http://dx.doi.org/10.1093/femsre/fuy027 Text en © FEMS 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review Article
Pohlschroder, Mechthild
Pfeiffer, Friedhelm
Schulze, Stefan
Halim, Mohd Farid Abdul
Archaeal cell surface biogenesis
title Archaeal cell surface biogenesis
title_full Archaeal cell surface biogenesis
title_fullStr Archaeal cell surface biogenesis
title_full_unstemmed Archaeal cell surface biogenesis
title_short Archaeal cell surface biogenesis
title_sort archaeal cell surface biogenesis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098224/
https://www.ncbi.nlm.nih.gov/pubmed/29912330
http://dx.doi.org/10.1093/femsre/fuy027
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