RNA triphosphatase is essential in Schizosaccharomyces pombe and Candida albicans

BACKGROUND: The first two steps in the capping of cellular mRNAs are catalyzed by the enzymes RNA triphosphatase and RNA guanylyltransferase. Although structural and mechanistic differences between fungal and mammalian RNA triphosphatases recommend this enzyme as a potential antifungal target, it ha...

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Detalles Bibliográficos
Autores principales: Pei, Yi, Schwer, Beate, Saiz, Julia, Fisher, Robert P, Shuman, Stewart
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60989/
https://www.ncbi.nlm.nih.gov/pubmed/11737862

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