Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide

Sodium thiosulfate (STS), first‐line treatment for calcific uremic arteriolopathy, causes a mild asymptomatic acidosis in many patients. However, severe, life‐threatening acidosis out of proportion with the expected acid load of STS may occur, potentially due to metabolism of STS to hydrogen sulfide...

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Detalles Bibliográficos
Autores principales: Hunt, Guenola M., Ryder, Hilary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099024/
https://www.ncbi.nlm.nih.gov/pubmed/30147912
http://dx.doi.org/10.1002/ccr3.1673
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author Hunt, Guenola M.
Ryder, Hilary F.
author_facet Hunt, Guenola M.
Ryder, Hilary F.
author_sort Hunt, Guenola M.
collection PubMed
description Sodium thiosulfate (STS), first‐line treatment for calcific uremic arteriolopathy, causes a mild asymptomatic acidosis in many patients. However, severe, life‐threatening acidosis out of proportion with the expected acid load of STS may occur, potentially due to metabolism of STS to hydrogen sulfide.
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spelling pubmed-60990242018-08-24 Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide Hunt, Guenola M. Ryder, Hilary F. Clin Case Rep Case Reports Sodium thiosulfate (STS), first‐line treatment for calcific uremic arteriolopathy, causes a mild asymptomatic acidosis in many patients. However, severe, life‐threatening acidosis out of proportion with the expected acid load of STS may occur, potentially due to metabolism of STS to hydrogen sulfide. John Wiley and Sons Inc. 2018-07-01 /pmc/articles/PMC6099024/ /pubmed/30147912 http://dx.doi.org/10.1002/ccr3.1673 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Hunt, Guenola M.
Ryder, Hilary F.
Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
title Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
title_full Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
title_fullStr Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
title_full_unstemmed Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
title_short Metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
title_sort metabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099024/
https://www.ncbi.nlm.nih.gov/pubmed/30147912
http://dx.doi.org/10.1002/ccr3.1673
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