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Genome Wide Distribution of Linker Histone H1.0 is Independent of MeCP2

Previous studies suggested that MeCP2 competes with linker histone H1, but this hypothesis has never been tested in vivo. Here, we performed ChIP-Seq of Flag-tagged-H1.0 in mouse forebrain excitatory neurons. Unexpectedly, Flag-H1.0 and MeCP2 occupied similar genomic regions and the Flag-H1.0 bindin...

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Detalles Bibliográficos
Autores principales:	Ito-Ishida, Aya, Yamalanchili, Hari K., Shao, Yingyao, Baker, Steven A., Heckman, Laura D., Lavery, Laura A., Kim, Ji-yoen, Lombardi, Laura M., Sun, Yaling, Liu, Zhandong, Zoghbi, Huda Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099063/ https://www.ncbi.nlm.nih.gov/pubmed/29802390 http://dx.doi.org/10.1038/s41593-018-0155-8

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