Cargando…
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
BACKGROUND: The search for an optimal experimental model in pharmacology is recently focused on (mini)pigs as they seem not only to be an alternative source of cells and tissues for xenotherapy but also an alternative species for studies on drug metabolism in man due to similarities between (mini) p...
Autores principales: | Soucek, Pavel, Zuber, Roman, Anzenbacherová, Eva, Anzenbacher, Pavel, Guengerich, F Peter |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60991/ https://www.ncbi.nlm.nih.gov/pubmed/11737866 http://dx.doi.org/10.1186/1471-2210-1-11 |
Ejemplares similares
-
Enzyme systems of detoxication – overview of recent approaches
por: Anzenbacher, Pavel, et al.
Publicado: (2008) -
Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5: Contribution of the Microbiome
por: Satka, Stefan, et al.
Publicado: (2022) -
Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences
por: Jourová, Lenka, et al.
Publicado: (2020) -
Gut microbiome affects the metabolism of metronidazole in mice through regulation of hepatic cytochromes P450 expression
por: Zemanová, Nina, et al.
Publicado: (2021) -
Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity
por: Krasulova, Kristyna, et al.
Publicado: (2017)