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Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone

Oleuropein aglycone, which is the major phenolic component of extra virgin olive oil, is gaining popularity and importance in scientific and public communities. This paper summarizes the structure properties, acquisition protocols, and biological activities of oleuropein aglycone. There are three hy...

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Autores principales: Xu, Fangxue, Li, Yujuan, Zheng, Mengmeng, Xi, Xiaozhi, Zhang, Xuelan, Han, Chunchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099103/
https://www.ncbi.nlm.nih.gov/pubmed/30151359
http://dx.doi.org/10.3389/fchem.2018.00239
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author Xu, Fangxue
Li, Yujuan
Zheng, Mengmeng
Xi, Xiaozhi
Zhang, Xuelan
Han, Chunchao
author_facet Xu, Fangxue
Li, Yujuan
Zheng, Mengmeng
Xi, Xiaozhi
Zhang, Xuelan
Han, Chunchao
author_sort Xu, Fangxue
collection PubMed
description Oleuropein aglycone, which is the major phenolic component of extra virgin olive oil, is gaining popularity and importance in scientific and public communities. This paper summarizes the structure properties, acquisition protocols, and biological activities of oleuropein aglycone. There are three hydrolytic methods used to obtain oleuropein aglycone from oleuropein-enzymatic hydrolysis, acid hydrolysis, and acetal hydrolysis. Enzymatic hydrolysis can be achieved with exogenous enzymes and endogenous enzymes. In addition, the diverse pharmacological effects of oleuropein aglycone are summaried. These pharmacological effects include anti-Alzheimer's disease, anti-breast cancer, anti-inflammatory, anti-hyperglycemic, anti-oxidative, and lipid-lowering properties. Therefore, we can use hydrolysis and biological activities to study oleuropein aglycone in the future.
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spelling pubmed-60991032018-08-27 Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone Xu, Fangxue Li, Yujuan Zheng, Mengmeng Xi, Xiaozhi Zhang, Xuelan Han, Chunchao Front Chem Chemistry Oleuropein aglycone, which is the major phenolic component of extra virgin olive oil, is gaining popularity and importance in scientific and public communities. This paper summarizes the structure properties, acquisition protocols, and biological activities of oleuropein aglycone. There are three hydrolytic methods used to obtain oleuropein aglycone from oleuropein-enzymatic hydrolysis, acid hydrolysis, and acetal hydrolysis. Enzymatic hydrolysis can be achieved with exogenous enzymes and endogenous enzymes. In addition, the diverse pharmacological effects of oleuropein aglycone are summaried. These pharmacological effects include anti-Alzheimer's disease, anti-breast cancer, anti-inflammatory, anti-hyperglycemic, anti-oxidative, and lipid-lowering properties. Therefore, we can use hydrolysis and biological activities to study oleuropein aglycone in the future. Frontiers Media S.A. 2018-08-13 /pmc/articles/PMC6099103/ /pubmed/30151359 http://dx.doi.org/10.3389/fchem.2018.00239 Text en Copyright © 2018 Xu, Li, Zheng, Xi, Zhang and Han. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Xu, Fangxue
Li, Yujuan
Zheng, Mengmeng
Xi, Xiaozhi
Zhang, Xuelan
Han, Chunchao
Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone
title Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone
title_full Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone
title_fullStr Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone
title_full_unstemmed Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone
title_short Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone
title_sort structure properties, acquisition protocols, and biological activities of oleuropein aglycone
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099103/
https://www.ncbi.nlm.nih.gov/pubmed/30151359
http://dx.doi.org/10.3389/fchem.2018.00239
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