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The Role of Histamine and Histamine Receptors in Mast Cell-Mediated Allergy and Inflammation: The Hunt for New Therapeutic Targets

Histamine and its receptors (H1R–H4R) play a crucial and significant role in the development of various allergic diseases. Mast cells are multifunctional bone marrow-derived tissue-dwelling cells that are the major producer of histamine in the body. H1R are expressed in many cells, including mast ce...

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Detalles Bibliográficos
Autores principales: Thangam, Elden Berla, Jemima, Ebenezer Angel, Singh, Himadri, Baig, Mirza Saqib, Khan, Mahejibin, Mathias, Clinton B., Church, Martin K., Saluja, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099187/
https://www.ncbi.nlm.nih.gov/pubmed/30150993
http://dx.doi.org/10.3389/fimmu.2018.01873

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