Endothelial Notch activation reshapes the angiocrine of sinusoidal endothelia to aggravate liver fibrosis and blunt regeneration in mice

Liver sinusoidal endothelial cells (LSECs) critically regulate liver homeostasis and diseases through angiocrine factors. Notch is critical in endothelial cells (ECs). In the current study, Notch signaling was activated by inducible EC‐specific expression of the Notch intracellular domain (NIC). We...

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Detalles Bibliográficos
Autores principales: Duan, Juan‐Li, Ruan, Bai, Yan, Xian‐Chun, Liang, Liang, Song, Ping, Yang, Zi‐Yan, Liu, Yuan, Dou, Ke‐Feng, Han, Hua, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099357/
https://www.ncbi.nlm.nih.gov/pubmed/29420858
http://dx.doi.org/10.1002/hep.29834

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