Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions

Herein, we introduce a new class of bench‐stable N‐heterocyclic carbene (NHC) nickel‐precatalysts for homogeneous nickel‐catalysis. The nickel(II) complexes are readily activated to Ni(0) in situ under mild conditions, via a proposed Heck‐type mechanism. The precatalysts are shown to facilitate carb...

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Detalles Bibliográficos
Autores principales: Strieth‐Kalthoff, Felix, Longstreet, Ashley R., Weber, Jessica M., Jamison, Timothy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099443/
https://www.ncbi.nlm.nih.gov/pubmed/30147804
http://dx.doi.org/10.1002/cctc.201800454
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author Strieth‐Kalthoff, Felix
Longstreet, Ashley R.
Weber, Jessica M.
Jamison, Timothy F.
author_facet Strieth‐Kalthoff, Felix
Longstreet, Ashley R.
Weber, Jessica M.
Jamison, Timothy F.
author_sort Strieth‐Kalthoff, Felix
collection PubMed
description Herein, we introduce a new class of bench‐stable N‐heterocyclic carbene (NHC) nickel‐precatalysts for homogeneous nickel‐catalysis. The nickel(II) complexes are readily activated to Ni(0) in situ under mild conditions, via a proposed Heck‐type mechanism. The precatalysts are shown to facilitate carbonyl‐ene, hydroalkenylation, and amination reactions.
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spelling pubmed-60994432018-08-24 Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions Strieth‐Kalthoff, Felix Longstreet, Ashley R. Weber, Jessica M. Jamison, Timothy F. ChemCatChem Full Papers Herein, we introduce a new class of bench‐stable N‐heterocyclic carbene (NHC) nickel‐precatalysts for homogeneous nickel‐catalysis. The nickel(II) complexes are readily activated to Ni(0) in situ under mild conditions, via a proposed Heck‐type mechanism. The precatalysts are shown to facilitate carbonyl‐ene, hydroalkenylation, and amination reactions. John Wiley and Sons Inc. 2018-05-02 2018-07-09 /pmc/articles/PMC6099443/ /pubmed/30147804 http://dx.doi.org/10.1002/cctc.201800454 Text en © 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Full Papers
Strieth‐Kalthoff, Felix
Longstreet, Ashley R.
Weber, Jessica M.
Jamison, Timothy F.
Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions
title Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions
title_full Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions
title_fullStr Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions
title_full_unstemmed Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions
title_short Bench‐Stable N‐Heterocyclic Carbene Nickel Precatalysts for C−C and C−N Bond‐Forming Reactions
title_sort bench‐stable n‐heterocyclic carbene nickel precatalysts for c−c and c−n bond‐forming reactions
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099443/
https://www.ncbi.nlm.nih.gov/pubmed/30147804
http://dx.doi.org/10.1002/cctc.201800454
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