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Variant‐specific and reciprocal Hsp40 functions in Hsp104‐mediated prion elimination

The amyloid‐based prions of Saccharomyces cerevisiae are heritable aggregates of misfolded proteins, passed to daughter cells following fragmentation by molecular chaperones including the J‐protein Sis1, Hsp70 and Hsp104. Overexpression of Hsp104 efficiently cures cell populations of the prion [PSI...

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Detalles Bibliográficos
Autores principales:	Astor, Michael T., Kamiya, Erina, Sporn, Zachary A., Berger, Scott E., Hines, Justin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099457/ https://www.ncbi.nlm.nih.gov/pubmed/29633387 http://dx.doi.org/10.1111/mmi.13966

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