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Characterization of a Synovial B Cell–Derived Recombinant Monoclonal Antibody Targeting Stromal Calreticulin in the Rheumatoid Joints

Rheumatoid arthritis (RA) is characterized by formation of synovial ectopic lymphoid structures (ELS) supporting B cell autoreactivity toward locally generated citrullinated (cit) antigens, including those contained in neutrophil extracellular traps (NETs). However, only a minority of RA-rmAbs from...

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Detalles Bibliográficos
Autores principales:	Corsiero, Elisa, Jagemann, Lucas, Perretti, Mauro, Pitzalis, Costantino, Bombardieri, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2018
Materias:	Clinical and Human Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099528/ https://www.ncbi.nlm.nih.gov/pubmed/30045972 http://dx.doi.org/10.4049/jimmunol.1800346

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