Interleukin-33: Its Emerging Role in Allergic Diseases

Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an impor...

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Detalles Bibliográficos
Autores principales: Ding, Wen, Zou, Gui-Lin, Zhang, Wei, Lai, Xing-Ning, Chen, Hou-Wen, Xiong, Li-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099536/
https://www.ncbi.nlm.nih.gov/pubmed/29987222
http://dx.doi.org/10.3390/molecules23071665
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author Ding, Wen
Zou, Gui-Lin
Zhang, Wei
Lai, Xing-Ning
Chen, Hou-Wen
Xiong, Li-Xia
author_facet Ding, Wen
Zou, Gui-Lin
Zhang, Wei
Lai, Xing-Ning
Chen, Hou-Wen
Xiong, Li-Xia
author_sort Ding, Wen
collection PubMed
description Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an important role in these refractory disorders, mainly by inducing T helper (Th) 2 immune responses. This article reviews the mobilization and biological function of IL-33 in allergic disorders, providing novel insights for addressing these hypersensitive conditions.
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spelling pubmed-60995362018-11-13 Interleukin-33: Its Emerging Role in Allergic Diseases Ding, Wen Zou, Gui-Lin Zhang, Wei Lai, Xing-Ning Chen, Hou-Wen Xiong, Li-Xia Molecules Review Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an important role in these refractory disorders, mainly by inducing T helper (Th) 2 immune responses. This article reviews the mobilization and biological function of IL-33 in allergic disorders, providing novel insights for addressing these hypersensitive conditions. MDPI 2018-07-09 /pmc/articles/PMC6099536/ /pubmed/29987222 http://dx.doi.org/10.3390/molecules23071665 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ding, Wen
Zou, Gui-Lin
Zhang, Wei
Lai, Xing-Ning
Chen, Hou-Wen
Xiong, Li-Xia
Interleukin-33: Its Emerging Role in Allergic Diseases
title Interleukin-33: Its Emerging Role in Allergic Diseases
title_full Interleukin-33: Its Emerging Role in Allergic Diseases
title_fullStr Interleukin-33: Its Emerging Role in Allergic Diseases
title_full_unstemmed Interleukin-33: Its Emerging Role in Allergic Diseases
title_short Interleukin-33: Its Emerging Role in Allergic Diseases
title_sort interleukin-33: its emerging role in allergic diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099536/
https://www.ncbi.nlm.nih.gov/pubmed/29987222
http://dx.doi.org/10.3390/molecules23071665
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