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Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †

This review highlights the utilization of dendron-polymer conjugates as building blocks for the fabrication of nanosized drug delivery vehicles. The examples given provide an overview of the evolution of these delivery platforms, from simple micellar containers to smart stimuli- responsive drug deli...

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Detalles Bibliográficos
Autores principales: Bolu, Burcu Sumer, Sanyal, Rana, Sanyal, Amitav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099537/
https://www.ncbi.nlm.nih.gov/pubmed/29958437
http://dx.doi.org/10.3390/molecules23071570
Descripción
Sumario:This review highlights the utilization of dendron-polymer conjugates as building blocks for the fabrication of nanosized drug delivery vehicles. The examples given provide an overview of the evolution of these delivery platforms, from simple micellar containers to smart stimuli- responsive drug delivery systems through their design at the macromolecular level. Variations in chemical composition and connectivity of the dendritic and polymeric segments provide a variety of self-assembled micellar nanostructures that embody desirable attributes of viable drug delivery systems.