Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †

This review highlights the utilization of dendron-polymer conjugates as building blocks for the fabrication of nanosized drug delivery vehicles. The examples given provide an overview of the evolution of these delivery platforms, from simple micellar containers to smart stimuli- responsive drug deli...

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Detalles Bibliográficos
Autores principales: Bolu, Burcu Sumer, Sanyal, Rana, Sanyal, Amitav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099537/
https://www.ncbi.nlm.nih.gov/pubmed/29958437
http://dx.doi.org/10.3390/molecules23071570
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author Bolu, Burcu Sumer
Sanyal, Rana
Sanyal, Amitav
author_facet Bolu, Burcu Sumer
Sanyal, Rana
Sanyal, Amitav
author_sort Bolu, Burcu Sumer
collection PubMed
description This review highlights the utilization of dendron-polymer conjugates as building blocks for the fabrication of nanosized drug delivery vehicles. The examples given provide an overview of the evolution of these delivery platforms, from simple micellar containers to smart stimuli- responsive drug delivery systems through their design at the macromolecular level. Variations in chemical composition and connectivity of the dendritic and polymeric segments provide a variety of self-assembled micellar nanostructures that embody desirable attributes of viable drug delivery systems.
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spelling pubmed-60995372018-11-13 Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates † Bolu, Burcu Sumer Sanyal, Rana Sanyal, Amitav Molecules Review This review highlights the utilization of dendron-polymer conjugates as building blocks for the fabrication of nanosized drug delivery vehicles. The examples given provide an overview of the evolution of these delivery platforms, from simple micellar containers to smart stimuli- responsive drug delivery systems through their design at the macromolecular level. Variations in chemical composition and connectivity of the dendritic and polymeric segments provide a variety of self-assembled micellar nanostructures that embody desirable attributes of viable drug delivery systems. MDPI 2018-06-28 /pmc/articles/PMC6099537/ /pubmed/29958437 http://dx.doi.org/10.3390/molecules23071570 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bolu, Burcu Sumer
Sanyal, Rana
Sanyal, Amitav
Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †
title Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †
title_full Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †
title_fullStr Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †
title_full_unstemmed Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †
title_short Drug Delivery Systems from Self-Assembly of Dendron-Polymer Conjugates †
title_sort drug delivery systems from self-assembly of dendron-polymer conjugates †
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099537/
https://www.ncbi.nlm.nih.gov/pubmed/29958437
http://dx.doi.org/10.3390/molecules23071570
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