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Carbazole Derivatives’ Binding to c-KIT G-Quadruplex DNA

The binding affinities of three carbazole derivatives to the intramolecular G-quadruplex (GQ) DNA formed by the sequence 5′-AGGGAGGGCGCTGGGAGGAGGG-3′, derived from the c-KIT 1 oncogene region, were investigated. All carbazole cationic ligands that differed in the substituents on the nitrogen atom we...

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Detalles Bibliográficos
Autores principales:	Głuszyńska, Agata, Juskowiak, Bernard, Kuta-Siejkowska, Martyna, Hoffmann, Marcin, Haider, Shozeb
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099540/ https://www.ncbi.nlm.nih.gov/pubmed/29747481 http://dx.doi.org/10.3390/molecules23051134

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