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Upregulation of UDP-Glucuronosyltransferases 1a1 and 1a7 Are Involved in Altered Puerarin Pharmacokinetics in Type II Diabetic Rats

Puerarin is an isoflavonoid extracted from Pueraria lobata roots, and displays a broad range of pharmacological activities, including antidiabetic activity. However, information about the pharmacokinetics of puerarin in diabetics is scarce. This study was conducted to investigate the difference in p...

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Detalles Bibliográficos
Autores principales: Dong, Songtao, Zhang, Maofan, Niu, Huimin, Jiang, Kunyu, Jiang, Jialei, Ma, Yinglin, Wang, Xin, Meng, Shengnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099598/
https://www.ncbi.nlm.nih.gov/pubmed/29925761
http://dx.doi.org/10.3390/molecules23061487