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Structural Divergence in O-GlcNAc Glycans Displayed on Epidermal Growth Factor-like Repeats of Mammalian Notch1
Extracellular O-GlcNAc is a novel class of modification catalyzed by epidermal growth factor-like (EGF)-domain specific O-GlcNAc transferase (EOGT). In mammals, EOGT is required for ligand-mediated Notch signaling for vascular development. Previous studies have revealed that O-GlcNAc in mammalian cu...
Autores principales: | Ogawa, Mitsutaka, Senoo, Yuya, Ikeda, Kazutaka, Takeuchi, Hideyuki, Okajima, Tetsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099671/ https://www.ncbi.nlm.nih.gov/pubmed/30018219 http://dx.doi.org/10.3390/molecules23071745 |
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