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Mitochondria-Targeting Small Molecules Effectively Prevent Cardiotoxicity Induced by Doxorubicin
Doxorubicin (Dox) is a chemotherapeutic agent widely used for the treatment of numerous cancers. However, the clinical use of Dox is limited by its unwanted cardiotoxicity. Mitochondrial dysfunction has been associated with Dox-induced cardiotoxicity. To mitigate Dox-related cardiotoxicity, consider...
Autores principales: | Shi, Wei, Deng, Hongkuan, Zhang, Jianyong, Zhang, Ying, Zhang, Xiufang, Cui, Guozhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099719/ https://www.ncbi.nlm.nih.gov/pubmed/29921817 http://dx.doi.org/10.3390/molecules23061486 |
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