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Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts

Roseroot (Rhodiola rosea L.) belongs to plants revealing adaptogenic properties, which are attributed to the presence of specific phenolic compounds and are reflected mainly as antioxidant activity. The aim of the present study was to determine the antioxidant and antibacterial activity of various p...

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Autores principales: Kosakowska, Olga, Bączek, Katarzyna, Przybył, Jarosław L., Pióro-Jabrucka, Ewelina, Czupa, Weronika, Synowiec, Alicja, Gniewosz, Małgorzata, Costa, Rosaria, Mondello, Luigi, Węglarz, Zenon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099734/
https://www.ncbi.nlm.nih.gov/pubmed/30022015
http://dx.doi.org/10.3390/molecules23071767
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author Kosakowska, Olga
Bączek, Katarzyna
Przybył, Jarosław L.
Pióro-Jabrucka, Ewelina
Czupa, Weronika
Synowiec, Alicja
Gniewosz, Małgorzata
Costa, Rosaria
Mondello, Luigi
Węglarz, Zenon
author_facet Kosakowska, Olga
Bączek, Katarzyna
Przybył, Jarosław L.
Pióro-Jabrucka, Ewelina
Czupa, Weronika
Synowiec, Alicja
Gniewosz, Małgorzata
Costa, Rosaria
Mondello, Luigi
Węglarz, Zenon
author_sort Kosakowska, Olga
collection PubMed
description Roseroot (Rhodiola rosea L.) belongs to plants revealing adaptogenic properties, which are attributed to the presence of specific phenolic compounds and are reflected mainly as antioxidant activity. The aim of the present study was to determine the antioxidant and antibacterial activity of various products obtained from R. rosea (underground organs as well as their aqueous and ethanolic dry extracts) in relation to the chemical profiles of phenolic and essential oil compounds. The chemical profiles were determined by High-performance Liquid Chromatography with a diode-array detector (HPLC-DAD) and Gas chromatography-mass spectrometry (GC-MS), antioxidant activity by (1,1-Diphenyl-2-picrylhydrazyl) Scavenging Capacity Assay (DPPH), (2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) Scavenging Capacity Assay (ABTS) and Ferric Reducing Antioxidant Power Assay (FRAP) and antimicrobial properties were expressed as minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) values following the broth microdilutions method. The results show that the investigated samples differed in terms of their chemical compositions and biological activities. The extracts were more abundant in phenolic compounds (salidroside, tyrosol, and rosavin derivatives) in comparison to dried underground organs. The content of the determined phenolics in the analyzed extracts was affected by the solvent used for extraction. The ethanolic extract was characterized by the highest content of these substances in comparison to the aqueous one and the dried raw material, especially with regard to rosavin (969.71 mg/100 g). In parallel, this extract showed the strongest antioxidant and antibacterial activity. However, dried R. rosea underground organs also revealed strong antibacterial effects against, for example, Staphylococcus strains.
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spelling pubmed-60997342018-11-13 Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts Kosakowska, Olga Bączek, Katarzyna Przybył, Jarosław L. Pióro-Jabrucka, Ewelina Czupa, Weronika Synowiec, Alicja Gniewosz, Małgorzata Costa, Rosaria Mondello, Luigi Węglarz, Zenon Molecules Article Roseroot (Rhodiola rosea L.) belongs to plants revealing adaptogenic properties, which are attributed to the presence of specific phenolic compounds and are reflected mainly as antioxidant activity. The aim of the present study was to determine the antioxidant and antibacterial activity of various products obtained from R. rosea (underground organs as well as their aqueous and ethanolic dry extracts) in relation to the chemical profiles of phenolic and essential oil compounds. The chemical profiles were determined by High-performance Liquid Chromatography with a diode-array detector (HPLC-DAD) and Gas chromatography-mass spectrometry (GC-MS), antioxidant activity by (1,1-Diphenyl-2-picrylhydrazyl) Scavenging Capacity Assay (DPPH), (2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) Scavenging Capacity Assay (ABTS) and Ferric Reducing Antioxidant Power Assay (FRAP) and antimicrobial properties were expressed as minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) values following the broth microdilutions method. The results show that the investigated samples differed in terms of their chemical compositions and biological activities. The extracts were more abundant in phenolic compounds (salidroside, tyrosol, and rosavin derivatives) in comparison to dried underground organs. The content of the determined phenolics in the analyzed extracts was affected by the solvent used for extraction. The ethanolic extract was characterized by the highest content of these substances in comparison to the aqueous one and the dried raw material, especially with regard to rosavin (969.71 mg/100 g). In parallel, this extract showed the strongest antioxidant and antibacterial activity. However, dried R. rosea underground organs also revealed strong antibacterial effects against, for example, Staphylococcus strains. MDPI 2018-07-18 /pmc/articles/PMC6099734/ /pubmed/30022015 http://dx.doi.org/10.3390/molecules23071767 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kosakowska, Olga
Bączek, Katarzyna
Przybył, Jarosław L.
Pióro-Jabrucka, Ewelina
Czupa, Weronika
Synowiec, Alicja
Gniewosz, Małgorzata
Costa, Rosaria
Mondello, Luigi
Węglarz, Zenon
Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts
title Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts
title_full Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts
title_fullStr Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts
title_full_unstemmed Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts
title_short Antioxidant and Antibacterial Activity of Roseroot (Rhodiola rosea L.) Dry Extracts
title_sort antioxidant and antibacterial activity of roseroot (rhodiola rosea l.) dry extracts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099734/
https://www.ncbi.nlm.nih.gov/pubmed/30022015
http://dx.doi.org/10.3390/molecules23071767
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