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Piplartine Analogues and Cytotoxic Evaluation against Glioblastoma

Piplartine (1) is an alkamide extracted from plants of the genus Piper which shows several pharmacological properties, including antitumor activity. To improve this activity, a series of analogues based on 1 have been synthesized by esterification and amidation using the 3,4,5-trimethoxycinnamic aci...

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Detalles Bibliográficos
Autores principales: da Nóbrega, Flávio Rogério, Ozdemir, Ozlem, Nascimento Sousa, Sheila Cristina S., Barboza, Joice Nascimento, Turkez, Hasan, de Sousa, Damião Pergentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099735/
https://www.ncbi.nlm.nih.gov/pubmed/29890617
http://dx.doi.org/10.3390/molecules23061382

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