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Cobalt-Catalyzed (Hetero)arylation of Saturated Cyclic Amines with Grignard Reagents

(Hetero)aryl substituted saturated cyclic amines are ubiquitous scaffolds in biologically active molecules. Metal-catalyzed cross-couplings between halogeno N-heterocycles and organometallic species are efficient and modular reactions to access these attractive scaffolds. An overview of our work con...

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Detalles Bibliográficos
Autores principales: Barré, Baptiste, Gonnard, Laurine, Guérinot, Amandine, Cossy, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099817/
https://www.ncbi.nlm.nih.gov/pubmed/29904007
http://dx.doi.org/10.3390/molecules23061449