Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles

The local environment is crucial for shaping the identities of tissue-resident macrophages (Mϕs). When hemorrhage occurs in damaged tissues, hemoglobin induces differentiation of anti-inflammatory Mϕs with reparative function. Mucosal bleeding is one of the pathological features of inflammatory bowe...

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Detalles Bibliográficos
Autores principales: Kayama, Hisako, Kohyama, Masako, Okuzaki, Daisuke, Motooka, Daisuke, Barman, Soumik, Okumura, Ryu, Muneta, Masato, Hoshino, Katsuaki, Sasaki, Izumi, Ise, Wataru, Matsuno, Hiroshi, Nishimura, Junichi, Kurosaki, Tomohiro, Nakamura, Shota, Arase, Hisashi, Kaisho, Tsuneyasu, Takeda, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099887/
https://www.ncbi.nlm.nih.gov/pubmed/30061415
http://dx.doi.org/10.1073/pnas.1808426115

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