Development of Conjugate Addition of Lithium Dialkylcuprates to Thiochromones: Synthesis of 2-Alkylthiochroman-4-ones and Additional Synthetic Applications

Lithium dialkylcuprates undergo conjugate addition to thiochromones to afford 2-alkylthiochroman-4-ones in good yields. This approach provide an efficient and general synthetic approach to privileged sulfur-containing structural motifs and valuable precursors for many pharmaceuticals, starting from...

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Detalles Bibliográficos
Autores principales: Bass, Shekinah A., Parker, Dynasty M., Bellinger, Tania J., Eaton, Aireal S., Dibble, Angelica S., Koroma, Kaata L., Sekyi, Sylvia A., Pollard, David A., Guo, Fenghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099951/
https://www.ncbi.nlm.nih.gov/pubmed/30011953
http://dx.doi.org/10.3390/molecules23071728

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