Modulation of Rat Hepatic CYP1A and 2C Activity by Honokiol and Magnolol: Differential Effects on Phenacetin and Diclofenac Pharmacokinetics In Vivo

Honokiol (2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol) and magnolol (4-Allyl-2-(5-allyl-2-hydroxy-phenyl)phenol) are the major active polyphenol constituents of Magnolia officinalis (Magnoliaceae) bark, which has been widely used in traditional Chinese medicine (Houpu Tang) for the treat...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Bum, Kim, Kyu-Sang, Ryu, Heon-Min, Hong, Seong-Ho, Kim, Bo-Kyoung, Kim, Dae-Duk, Park, Jin Woo, Yoon, In-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100004/
https://www.ncbi.nlm.nih.gov/pubmed/29914211
http://dx.doi.org/10.3390/molecules23061470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100004/
https://www.ncbi.nlm.nih.gov/pubmed/29914211
http://dx.doi.org/10.3390/molecules23061470

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