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Modulation of Rat Hepatic CYP1A and 2C Activity by Honokiol and Magnolol: Differential Effects on Phenacetin and Diclofenac Pharmacokinetics In Vivo
Honokiol (2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol) and magnolol (4-Allyl-2-(5-allyl-2-hydroxy-phenyl)phenol) are the major active polyphenol constituents of Magnolia officinalis (Magnoliaceae) bark, which has been widely used in traditional Chinese medicine (Houpu Tang) for the treat...
Autores principales: | Kim, Sang-Bum, Kim, Kyu-Sang, Ryu, Heon-Min, Hong, Seong-Ho, Kim, Bo-Kyoung, Kim, Dae-Duk, Park, Jin Woo, Yoon, In-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100004/ https://www.ncbi.nlm.nih.gov/pubmed/29914211 http://dx.doi.org/10.3390/molecules23061470 |
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