Combining Albumin-Binding Properties and Interaction with Pemetrexed to Improve the Tissue Distribution of Radiofolates

Folic-acid-based radioconjugates have been developed for nuclear imaging of folate receptor (FR)-positive tumors; however, high renal uptake was unfavorable in view of a therapeutic application. Previously, it was shown that pre-injection of pemetrexed (PMX) increased the tumor-to-kidney ratio of ra...

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Detalles Bibliográficos
Autores principales: Müller, Cristina, Guzik, Patrycja, Siwowska, Klaudia, Cohrs, Susan, Schmid, Raffaella M., Schibli, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100011/
https://www.ncbi.nlm.nih.gov/pubmed/29914162
http://dx.doi.org/10.3390/molecules23061465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100011/
https://www.ncbi.nlm.nih.gov/pubmed/29914162
http://dx.doi.org/10.3390/molecules23061465

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