Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy

Synthesis of the sex pheromone of the tea tussock moth in 33% overall yield over 10 steps was achieved. Moreover, the chiral pool concept was applied in the asymmetric synthesis. The synthesis used a chemical available on a large-scale from recycling of wastewater from the steroid industry. The carb...

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Autores principales: Zhang, Hong-Li, Sun, Zhi-Feng, Zhou, Lu-Nan, Liu, Lu, Zhang, Tao, Du, Zhen-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100017/
https://www.ncbi.nlm.nih.gov/pubmed/29867014
http://dx.doi.org/10.3390/molecules23061347
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author Zhang, Hong-Li
Sun, Zhi-Feng
Zhou, Lu-Nan
Liu, Lu
Zhang, Tao
Du, Zhen-Ting
author_facet Zhang, Hong-Li
Sun, Zhi-Feng
Zhou, Lu-Nan
Liu, Lu
Zhang, Tao
Du, Zhen-Ting
author_sort Zhang, Hong-Li
collection PubMed
description Synthesis of the sex pheromone of the tea tussock moth in 33% overall yield over 10 steps was achieved. Moreover, the chiral pool concept was applied in the asymmetric synthesis. The synthesis used a chemical available on a large-scale from recycling of wastewater from the steroid industry. The carbon skeleton was constructed using the C4+C5+C8 strategy. Based on this strategy, the original chiral center was totally retained.
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spelling pubmed-61000172018-11-13 Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy Zhang, Hong-Li Sun, Zhi-Feng Zhou, Lu-Nan Liu, Lu Zhang, Tao Du, Zhen-Ting Molecules Article Synthesis of the sex pheromone of the tea tussock moth in 33% overall yield over 10 steps was achieved. Moreover, the chiral pool concept was applied in the asymmetric synthesis. The synthesis used a chemical available on a large-scale from recycling of wastewater from the steroid industry. The carbon skeleton was constructed using the C4+C5+C8 strategy. Based on this strategy, the original chiral center was totally retained. MDPI 2018-06-04 /pmc/articles/PMC6100017/ /pubmed/29867014 http://dx.doi.org/10.3390/molecules23061347 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Hong-Li
Sun, Zhi-Feng
Zhou, Lu-Nan
Liu, Lu
Zhang, Tao
Du, Zhen-Ting
Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy
title Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy
title_full Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy
title_fullStr Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy
title_full_unstemmed Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy
title_short Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy
title_sort synthesis of the sex pheromone of the tea tussock moth based on a resource chemistry strategy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100017/
https://www.ncbi.nlm.nih.gov/pubmed/29867014
http://dx.doi.org/10.3390/molecules23061347
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