Cargando…
Antibodies towards Tyrosine Amyloid-Like Fibrils Allow Toxicity Modulation and Cellular Imaging of the Assemblies
The amino acid tyrosine forms cytotoxic amyloid-like fibrils by molecular self-assembly. However, the production of antibodies towards tyrosine assemblies, reflecting their presentation to the immune system, was not demonstrated yet. Here, we describe the production of antibodies that specifically r...
Autores principales: | Zaguri, Dor, Kreiser, Topaz, Shaham-Niv, Shira, Gazit, Ehud |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100058/ https://www.ncbi.nlm.nih.gov/pubmed/29861432 http://dx.doi.org/10.3390/molecules23061273 |
Ejemplares similares
-
Branched-Chain Amino Acid Assembly into Amyloid-like Fibrils Provides a New Paradigm for Maple Syrup Urine Disease Pathology
por: Kreiser, Topaz, et al.
Publicado: (2023) -
Induction of retinopathy by fibrillar oxalate assemblies
por: Zaguri, Dor, et al.
Publicado: (2020) -
Extension of the generic amyloid hypothesis to nonproteinaceous metabolite assemblies
por: Shaham-Niv, Shira, et al.
Publicado: (2015) -
Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation
por: Laor, Dana, et al.
Publicado: (2019) -
Seeding of proteins into amyloid structures by metabolite assemblies may clarify certain unexplained epidemiological associations
por: Sade, Dorin, et al.
Publicado: (2018)