Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata

A novel isoquinoline alkaloid, mahimbrine A, possessing a rare benzotropolone framing scaffold, was isolated from the endemic plant of Mahonia imbricata. Its structure was established on the basis of extensive spectroscopic analysis. A plausible biosynthetic route of mahimbrine A was proposed. Mahim...

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Autores principales: Zhang, Mao-Sheng, Deng, Yan, Fu, Shao-Bin, Guo, Da-Le, Xiao, Shi-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100064/
https://www.ncbi.nlm.nih.gov/pubmed/29949909
http://dx.doi.org/10.3390/molecules23071539
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author Zhang, Mao-Sheng
Deng, Yan
Fu, Shao-Bin
Guo, Da-Le
Xiao, Shi-Ji
author_facet Zhang, Mao-Sheng
Deng, Yan
Fu, Shao-Bin
Guo, Da-Le
Xiao, Shi-Ji
author_sort Zhang, Mao-Sheng
collection PubMed
description A novel isoquinoline alkaloid, mahimbrine A, possessing a rare benzotropolone framing scaffold, was isolated from the endemic plant of Mahonia imbricata. Its structure was established on the basis of extensive spectroscopic analysis. A plausible biosynthetic route of mahimbrine A was proposed. Mahimbrine A showed no antimicrobial activity at the concentration of 1 mg/mL.
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spelling pubmed-61000642018-11-13 Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata Zhang, Mao-Sheng Deng, Yan Fu, Shao-Bin Guo, Da-Le Xiao, Shi-Ji Molecules Article A novel isoquinoline alkaloid, mahimbrine A, possessing a rare benzotropolone framing scaffold, was isolated from the endemic plant of Mahonia imbricata. Its structure was established on the basis of extensive spectroscopic analysis. A plausible biosynthetic route of mahimbrine A was proposed. Mahimbrine A showed no antimicrobial activity at the concentration of 1 mg/mL. MDPI 2018-06-26 /pmc/articles/PMC6100064/ /pubmed/29949909 http://dx.doi.org/10.3390/molecules23071539 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Mao-Sheng
Deng, Yan
Fu, Shao-Bin
Guo, Da-Le
Xiao, Shi-Ji
Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata
title Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata
title_full Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata
title_fullStr Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata
title_full_unstemmed Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata
title_short Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata
title_sort mahimbrine a, a novel isoquinoline alkaloid bearing a benzotropolone moiety from mahonia imbricata
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100064/
https://www.ncbi.nlm.nih.gov/pubmed/29949909
http://dx.doi.org/10.3390/molecules23071539
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